Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Hydralazine Injection Generic Name & Formulations
Legal Class
Rx
General Description
Hydralazine (as HCl) 20mg/mL; IM or IV inj; contains parabens.
Pharmacological Class
Vasodilator.
See Also
How Supplied
Contact supplier.
Manufacturer
Hydralazine Injection Indications
Indications
Severe essential hypertension when oral therapy not feasible or there is an urgent need to lower blood pressure.
Hydralazine Injection Dosage and Administration
Adult
Monitor BP closely. 20–40mg; repeat as needed. Advanced renal damage: reduce dose.
Children
Not recommended; doses of 1.7–3.5mg/kg per day in 4–6 divided doses have been used.
Hydralazine Injection Contraindications
Contraindications
Coronary artery disease. Mitral valve disease.
Hydralazine Injection Boxed Warnings
Not Applicable
Hydralazine Injection Warnings/Precautions
Warnings/Precautions
Suspected coronary artery disease. Cerebrovascular accidents. Aortic aneurysm. Increased intracranial pressure. Renal disease. Treat paresthesias and/or numbness with pyridoxine. Discontinue if blood dyscrasias occur. Obtain CBC and ANA titer periodically; consider discontinuing if SLE occurs. Surgery. Pregnancy (Cat.C). Nursing mothers.
Hydralazine Injection Pharmacokinetics
See Literature
Hydralazine Injection Interactions
Interactions
Caution with MAOIs. Profound hypotension with potent parenteral antihypertensives (eg, diazoxide). Antagonized by NSAIDs. May block epinephrine.
Hydralazine Injection Adverse Reactions
Adverse Reactions
Headache, anorexia, GI disturbances, palpitations, edema, flushing, nasal congestion, lacrimation, rash, tachycardia, angina, orthostatic hypotension, blood dyscrasias, peripheral neuritis, SLE.
Hydralazine Injection Clinical Trials
See Literature
Hydralazine Injection Note
Notes
Formerly known under the brand names Apresoline (inj, tabs); Dralzine (tabs).
Hydralazine Injection Patient Counseling
See Literature
