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Gonitro Generic Name & Formulations
Legal Class
Rx
General Description
Nitroglycerin 400mcg; per pkt; sublingual powder.
Pharmacological Class
Nitrate.
How Supplied
Pwd pkts—12, 36, 96
Manufacturer
Generic Availability
NO
Gonitro Indications
Indications
Acute relief of angina attack. Acute prophylaxis of angina pectoris.
Gonitro Dosage and Administration
Adult
Treatment: 1 or 2 packets (400mcg/packet) sublingually at onset, may give 1 additional packet every 5 mins as needed; max 3 packets in 15 mins. Prophylaxis: 5–10 mins before activity.
Children
Not established.
Gonitro Contraindications
Contraindications
Concomitant PDE-5 inhibitors (eg, avanafil, sildenafil, tadalafil, vardenafil), soluble guanylate cyclase stimulators (eg, riociguat). Severe anemia. Increased intracranial pressure. Acute circulatory failure or shock.
Gonitro Boxed Warnings
Not Applicable
Gonitro Warnings/Precautions
Warnings/Precautions
Hypotensive (constrictive pericarditis, aortic or mitral stenosis) or volume depleted. Hypertrophic obstructive cardiomyopathy. Use lowest effective dose. Elderly. Pregnancy. Nursing mothers.
Gonitro Pharmacokinetics
See Literature
Gonitro Interactions
Interactions
See Contraindications. Hypotension potentiated by PDE-5 inhibitors, riociguat, antihypertensives, beta-adrenergic blockers, calcium channel blockers. Potentiated by high-dose aspirin. May antagonize tissue-type plasminogen activators (t-PA). Avoid ergotamine and related drugs; monitor if unavoidable.
Gonitro Adverse Reactions
Adverse Reactions
Headache, dizziness, paresthesia, hypotension.
Gonitro Clinical Trials
See Literature
Gonitro Note
Not Applicable
Gonitro Patient Counseling
See Literature
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