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Diuril Inj Generic Name & Formulations
Legal Class
Rx
General Description
Chlorothiazide (as sodium) 500mg/vial; pwd for IV inj after reconstitution; contains mannitol.
Pharmacological Class
Diuretic (thiazide).
How Supplied
Vial—1
Manufacturer
Diuril Inj Indications
Indications
Edema.
Diuril Inj Dosage and Administration
Adult
0.5–1g IV once or twice daily.
Children
Not recommended.
Diuril Inj Contraindications
Contraindications
Anuria. Sulfonamide allergy.
Diuril Inj Boxed Warnings
Not Applicable
Diuril Inj Warnings/Precautions
Warnings/Precautions
Renal or hepatic impairment. Arrhythmias. Diabetes. Gout. Asthma. SLE. Postsympathectomy. Excessive fluid loss. Monitor electrolytes, BUN (if high). Potassium supplements or K+ -sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Pregnancy (Cat.C). Nursing mothers: not recommended.
Diuril Inj Pharmacokinetics
See Literature
Diuril Inj Interactions
Interactions
Digitalis, lithium toxicity. Adjust antidiabetic, antigout medications. Antagonized by NSAIDs. ACTH, corticosteroids, amphotericin B increase hypokalemia risk. Hyperglycemia, hyperuricemia more likely with diazoxide. NSAIDs may cause renal failure. May potentiate nondepolarizing muscle relaxants, other antihypertensives. Hypotension with CNS depressants. May interfere with parathyroid tests.
Diuril Inj Adverse Reactions
Adverse Reactions
Electrolyte disorders (especially hypokalemia), hyperglycemia, hyperuricemia, photosensitivity, orthostatic hypotension, GI disturbances, adverse lipid values.
Diuril Inj Clinical Trials
See Literature
Diuril Inj Note
Not Applicable
Diuril Inj Patient Counseling
See Literature
