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Colestid Tablets Generic Name & Formulations
Legal Class
Rx
General Description
Colestipol HCl (micronized) 1g.
Pharmacological Class
Bile acid sequestrant.
See Also
How Supplied
Unflavored 5g pkt—30, 90; Bulk—300g, 500g (w. scoop); Flavored 7.5g pkt—60; Bulk—450g (w. scoop); Tabs—120
Manufacturer
Colestid Tablets Indications
Indications
Adjunct to diet to lower elevated serum total-C and LDL-C in primary hypercholesterolemia.
Colestid Tablets Dosage and Administration
Adult
Do not crush, chew, or cut. Take with adequate fluids. Initially 2g once or twice daily, then increase by 2g once or twice daily at 1–2 month intervals. Usual maintenance: 2–16g/day in 1 or more divided doses.
Children
Not established.
Colestid Tablets Contraindications
Not Applicable
Colestid Tablets Boxed Warnings
Not Applicable
Colestid Tablets Warnings/Precautions
Warnings/Precautions
Obtain baseline serum cholesterol, LDL-C, and triglycerides, and monitor during therapy. Consider reducing dose, discontinuing, or alternative therapy if significant increase in triglycerides occur. May need Vit. A, D and K supplementation with long-term therapy. Exclude secondary causes of hypercholesterolemia (eg, hypothyroidism, diabetes, nephrotic syndrome, dysproteinemias, obstructive liver disease, alcoholism). Constipation; increase fluid/fiber intake or add a stool softener. Hemorrhoids. Phenylketonurics (flavored Colestid). Monitor thyroid function. Pregnancy. Nursing mothers.
Colestid Tablets Pharmacokinetics
See Literature
Colestid Tablets Interactions
Interactions
Reduces absorption of folic acid, fat soluble vitamins, thiazides, furosemide, tetracycline, penicillin G, gemfibrozil, mycophenolic acid, others; monitor digitalis, propranolol; give other drugs at least 1hr before or 4hrs after. May affect absorption of oral phosphate supplements, hydrocortisone.
Colestid Tablets Adverse Reactions
Adverse Reactions
Constipation, fecal impaction, aggravated hemorrhoids, abdominal pain/cramp, gas, indigestion, heartburn, diarrhea, nausea, vomiting, Vit. A, D, K deficiencies or hyperchloremic acidosis with prolonged use.
Colestid Tablets Clinical Trials
See Literature
Colestid Tablets Note
Not Applicable
Colestid Tablets Patient Counseling
See Literature
