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Colestid Generic Name & Formulations
Legal Class
Rx
General Description
Colestipol HCl 5g/pkt or scoop; granules; orange flavored (contains aspartame, phenylalanine) or unflavored.
Pharmacological Class
Bile acid sequestrant.
See Also
How Supplied
Unflavored 5g pkt—30, 90; Bulk—300g, 500g (w. scoop); Flavored 7.5g pkt—60; Bulk—450g (w. scoop); Tabs—120
Manufacturer
Colestid Indications
Indications
Adjunct to diet to lower elevated serum total-C and LDL-C in primary hypercholesterolemia.
Colestid Dosage and Administration
Adult
5g–30g daily once or in divided doses mixed with liquid.
Children
Not established.
Colestid Contraindications
Not Applicable
Colestid Boxed Warnings
Not Applicable
Colestid Warnings/Precautions
Warnings/Precautions
Obtain baseline serum cholesterol, LDL-C, and triglycerides, and monitor during therapy. Consider reducing dose, discontinuing, or alternative therapy if significant increase in triglycerides occur. May need Vit. A, D and K supplementation with long-term therapy. Exclude secondary causes of hypercholesterolemia (eg, hypothyroidism, diabetes, nephrotic syndrome, dysproteinemias, obstructive liver disease, alcoholism). Constipation; increase fluid/fiber intake or add a stool softener. Hemorrhoids. Phenylketonurics (flavored Colestid). Monitor thyroid function. Pregnancy. Nursing mothers.
Colestid Pharmacokinetics
See Literature
Colestid Interactions
Interactions
Reduces absorption of folic acid, fat soluble vitamins, thiazides, furosemide, tetracycline, penicillin G, gemfibrozil, mycophenolic acid, others; monitor digitalis, propranolol; give other drugs at least 1hr before or 4hrs after. May affect absorption of oral phosphate supplements, hydrocortisone.
Colestid Adverse Reactions
Adverse Reactions
Constipation, fecal impaction, aggravated hemorrhoids, abdominal pain/cramp, gas, indigestion, heartburn, diarrhea, nausea, vomiting, Vit. A, D, K deficiencies or hyperchloremic acidosis with prolonged use.
Colestid Clinical Trials
See Literature
Colestid Note
Not Applicable
Colestid Patient Counseling
See Literature
