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Cardene Iv Generic Name & Formulations
Legal Class
Rx
General Description
Nicardipine HCl 2.5mg/mL; soln for slow IV infusion (after dilution to 0.1mg/mL).
Pharmacological Class
Calcium channel blocker (CCB) (dihydropyridine).
See Also
How Supplied
Caps 20mg, 30mg—contact supplier; IV (10mL amps)—10; Premixed—200mL
Manufacturer
Cardene Iv Indications
Indications
Short-term treatment of hypertension when oral therapy is not feasible or desirable.
Cardene Iv Dosage and Administration
Adult
Individualize; see full labeling.
Children
<18yrs: not established.
Cardene Iv Contraindications
Contraindications
Advanced aortic stenosis.
Cardene Iv Boxed Warnings
Not Applicable
Cardene Iv Warnings/Precautions
Warnings/Precautions
Angina. Heart failure. Acute cerebral infarction or hemorrhage. Hepatic or renal impairment. Pheochromocytoma. For caps: measure blood pressure (BP) 1–2 hrs and 8 hrs after dosing. For IV: monitor BP before and during infusion; avoid rapid or excessive reductions, intra-arterial administration or extravasation; switch to oral form when possible. Pregnancy (Cat.C). Nursing mothers: not recommended.
Cardene Iv Pharmacokinetics
See Literature
Cardene Iv Interactions
Interactions
Potentiated by cimetidine. Increases serum levels of cyclosporine, tacrolimus; monitor and adjust its dose. Possibly potentiates digoxin; monitor.
Cardene Iv Adverse Reactions
Adverse Reactions
Increased angina, flushing (caps), headache, pedal edema, asthenia, dizziness, somnolence (caps), tachycardia, GI upset, sweating; ECG abnormalities, orthostatic hypotension, ventricular extrasystoles, local reactions (inj).
Cardene Iv Clinical Trials
See Literature
Cardene Iv Note
Not Applicable
Cardene Iv Patient Counseling
See Literature
