Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Bumetanide Injection Generic Name & Formulations
Legal Class
Rx
General Description
Bumetanide 0.25mg/mL; contains benzyl alcohol.
Pharmacological Class
Diuretic (loop).
How Supplied
Contact supplier
Manufacturer
Bumetanide Injection Indications
Indications
Edema.
Bumetanide Injection Dosage and Administration
Adult
Initially 0.5–1mg IM or IV. May give 1–2 more doses at 2–3 hour intervals; max 10mg/day.
Children
<18yrs: not established.
Bumetanide Injection Contraindications
Contraindications
Anuria. Infants. Hepatic coma. Severe electrolyte depletion.
Bumetanide Injection Boxed Warnings
Not Applicable
Bumetanide Injection Warnings/Precautions
Warnings/Precautions
Hepatic cirrhosis. Ascites. Progressive renal disease. Gout. Diabetes. Postsympathectomy. Monitor electrolytes, blood, liver function. May need K+ supplementation. K+ losing nephropathy. Discontinue if renal dysfunction progresses. Aldosterone excess. Ventricular arrhythmias. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.
Bumetanide Injection Pharmacokinetics
See Literature
Bumetanide Injection Interactions
Interactions
May increase digitalis, lithium toxicity. Hypokalemia with digitalis, diuretics in CHF. Alcohol, CNS depressants increase orthostatic hypotension. Avoid probenecid, indomethacin. Ototoxicity may be potentiated with aminoglycosides.
Bumetanide Injection Adverse Reactions
Adverse Reactions
Muscle cramps, dizziness, hypotension, headache, nausea, encephalopathy, ototoxicity, rash, fluid or electrolyte imbalance, hyperglycemia, hyperuricemia, blood dyscrasias.
Bumetanide Injection Clinical Trials
See Literature
Bumetanide Injection Note
Notes
Formerly known under the brand name Bumex.
Bumetanide Injection Patient Counseling
See Literature
