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Bumetanide Generic Name & Formulations
Legal Class
Rx
General Description
Bumetanide 0.5mg, 1mg, 2mg; scored tabs.
Pharmacological Class
Diuretic (loop).
How Supplied
Contact supplier
Manufacturer
Bumetanide Indications
Indications
Edema.
Bumetanide Dosage and Administration
Adult
0.5mg–2mg daily; max 10mg daily. Intermittent dosing optimal.
Children
<18yrs: not established.
Bumetanide Contraindications
Contraindications
Anuria. Hepatic coma. Severe electrolyte depletion.
Bumetanide Boxed Warnings
Not Applicable
Bumetanide Warnings/Precautions
Warnings/Precautions
Hepatic cirrhosis. Ascites. Sulfonamide allergy. Progressive renal disease. Gout. Diabetes. Postsympathectomy. Monitor electrolytes, blood, liver function. Potassium supplementation may be needed. Potassium-losing nephropathy. Aldosterone excess. Discontinue if renal dysfunction progresses. Ventricular arrhythmias. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.
Bumetanide Pharmacokinetics
See Literature
Bumetanide Interactions
Interactions
May increase digitalis, lithium toxicity. Hypokalemia with digitalis, diuretics in CHF. Alcohol, CNS depressants may increase orthostatic hypotension. Avoid probenecid, indomethacin. Ototoxicity may be potentiated with aminoglycosides.
Bumetanide Adverse Reactions
Adverse Reactions
Muscle cramps, dizziness, hypotension, headache, nausea, encephalopathy, ototoxicity, rash, fluid or electrolyte imbalance, hyperglycemia, hyperuricemia, blood dyscrasias.
Bumetanide Clinical Trials
See Literature
Bumetanide Note
Notes
Formerly known under the brand name Bumex.
Bumetanide Patient Counseling
See Literature
