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Bayer, Aspirin Regimen Generic Name & Formulations
Legal Class
OTC
General Description
Aspirin 81mg tabs, 325mg caplets; e-c.
Pharmacological Class
Antiplatelet.
See Also
How Supplied
Aspirin Regimen 81mg—32, 120, 180; Aspirin Regimen 325mg—100; Children's—36; Bayer Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200; Gelcaps—40, 80
Manufacturer
Bayer, Aspirin Regimen Indications
Indications
To reduce combined risk of death and nonfatal stroke after ischemic stroke or TIA. To reduce risk of vascular mortality in suspected acute MI. To reduce combined risk of death and nonfatal MI after MI or unstable angina pectoris. To reduce combined risk of MI and sudden death in chronic stable angina. Revascularization procedures.
Bayer, Aspirin Regimen Dosage and Administration
Adult
Ischemic stroke and TIA: 50–325mg once daily. Suspected acute MI: 160–162.5mg once daily (start as soon as MI suspected) then for at least 30 days post-MI. Prevention of recurrent MI, unstable angina pectoris, chronic stable angina: 75–325mg once daily. Coronary artery bypass graft: 325mg once daily (start 6hrs after procedure) for 1yr. Percutaneous transluminal coronary angioplasty: 325mg 2 hours before surgery, then 160–325mg once daily. Carotid endarterectomy: 80mg once daily to 650mg twice daily (start before surgery).
Children
Not recommended.
Bayer, Aspirin Regimen Contraindications
Contraindications
NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.
Bayer, Aspirin Regimen Boxed Warnings
Not Applicable
Bayer, Aspirin Regimen Warnings/Precautions
Warnings/Precautions
History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.
Bayer, Aspirin Regimen Pharmacokinetics
See Literature
Bayer, Aspirin Regimen Interactions
Interactions
Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.
Bayer, Aspirin Regimen Adverse Reactions
Adverse Reactions
GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.
Bayer, Aspirin Regimen Clinical Trials
See Literature
Bayer, Aspirin Regimen Note
Not Applicable
Bayer, Aspirin Regimen Patient Counseling
See Literature
