Bayer

— THERAPEUTIC CATEGORIES —
  • Arthritis/rheumatic disorders
  • Nonnarcotic analgesics
  • Thromboembolic disorders

Bayer Generic Name & Formulations

General Description

Aspirin 325mg; tabs; caplets; gelcaps.

Pharmacological Class

Salicylate.

How Supplied

Ext Str tabs, caplets, Plus—50; Ext Str gelcaps—40, 80; Bayer Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200

Bayer Indications

Indications

Arthritic and rheumatic conditions.

Bayer Dosage and Administration

Adult

Rheumatoid arthritis, arthritis and pleurisy of SLE: initially 3g daily in divided doses; target plasma salicylate level 150–300mcg/mL. Osteoarthritis: up to 3g/day in divided doses. Spondyloarthropathies: up to 4g/day in divided doses.

Children

JRA: initially 90–130mg/kg per day in divided doses; target plasma salicylate level 150–300mcg/mL.

Bayer Contraindications

Contraindications

NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.

Bayer Boxed Warnings

Not Applicable

Bayer Warnings/Precautions

Warnings/Precautions

History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.

Bayer Pharmacokinetics

See Literature

Bayer Interactions

Interactions

Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.

Bayer Adverse Reactions

Adverse Reactions

GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.

Bayer Clinical Trials

See Literature

Bayer Note

Not Applicable

Bayer Patient Counseling

See Literature

Bayer Generic Name & Formulations

General Description

Aspirin 325mg; tabs; caplets; gelcaps.

Pharmacological Class

Salicylate.

How Supplied

Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200; Gelcaps—40, 80; Ext Str tabs, caplets, Plus—50; Ext Str Gelcaps—40, 80; Children's—36

Bayer Indications

Indications

Pain. Fever.

Bayer Dosage and Administration

Adult

325–650mg every 4hrs.

Children

Use chewable tabs.

Bayer Contraindications

Contraindications

NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.

Bayer Boxed Warnings

Not Applicable

Bayer Warnings/Precautions

Warnings/Precautions

History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.

Bayer Pharmacokinetics

See Literature

Bayer Interactions

Interactions

Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.

Bayer Adverse Reactions

Adverse Reactions

GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.

Bayer Clinical Trials

See Literature

Bayer Note

Not Applicable

Bayer Patient Counseling

See Literature

Bayer Generic Name & Formulations

General Description

Aspirin 325mg; tabs; caplets; gelcaps.

Pharmacological Class

Antiplatelet.

How Supplied

Aspirin Regimen 81mg—32, 120, 180; Aspirin Regimen 325mg—100; Children's—36; Bayer Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200; Gelcaps—40, 80

Bayer Indications

Indications

To reduce combined risk of death and nonfatal stroke after ischemic stroke or TIA. To reduce risk of vascular mortality in suspected acute MI. To reduce combined risk of death and nonfatal MI after MI or unstable angina pectoris. To reduce combined risk of MI and sudden death in chronic stable angina. Revascularization procedures.

Bayer Dosage and Administration

Adult

Ischemic stroke and TIA: 50–325mg once daily. Suspected acute MI: 160–162.5mg once daily (start as soon as MI suspected) then for at least 30 days post-MI. Prevention of recurrent MI, unstable angina pectoris, chronic stable angina: 75–325mg once daily. Coronary artery bypass graft: 325mg once daily (start 6hrs after procedure) for 1yr. Percutaneous transluminal coronary angioplasty: 325mg 2 hours before surgery, then 160–325mg once daily. Carotid endarterectomy: 80mg once daily to 650mg twice daily (start before surgery).

Children

Not recommended.

Bayer Contraindications

Contraindications

NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.

Bayer Boxed Warnings

Not Applicable

Bayer Warnings/Precautions

Warnings/Precautions

History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.

Bayer Pharmacokinetics

See Literature

Bayer Interactions

Interactions

Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.

Bayer Adverse Reactions

Adverse Reactions

GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.

Bayer Clinical Trials

See Literature

Bayer Note

Not Applicable

Bayer Patient Counseling

See Literature