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Diphenhydramine Injection Generic Name & Formulations
Legal Class
Rx
General Description
Diphenhydramine HCl 50mg/mL; for IV or IM inj.
Pharmacological Class
Antihistamine.
How Supplied
Caps—24, 48; Tabs—24, 48, 100; Dye-free softgels—24; Allergy Liq—4oz, 8oz; Dye-free Liq—4oz; Inj—contact supplier
Manufacturer
Diphenhydramine Injection Indications
Indications
Allergic disorders where oral form is impractical or contraindicated. Adjunct in anaphylaxis. Allergic reactions to blood or plasma.
Diphenhydramine Injection Dosage and Administration
Adult
10–50mg IV or deep IM; max 400mg/day.
Children
Neonates: not recommended. Others: 5mg/kg per day in 4 divided doses IV or deep IM; max 300mg daily in 4 divided doses.
Diphenhydramine Injection Contraindications
Contraindications
Neonates. Premature infants. Acute asthma. Concomitant diphenhydramine products (including topicals).
Diphenhydramine Injection Boxed Warnings
Not Applicable
Diphenhydramine Injection Warnings/Precautions
Warnings/Precautions
Asthma and lower respiratory disorders. Glaucoma. Hyperthyroidism. Hypertension. Cardiovascular disease. GI or urinary obstruction. Sodium-restricted diet. Children. Pregnancy (Cat.B in 3rd trimester): not recommended. Nursing mothers.
Diphenhydramine Injection Pharmacokinetics
See Literature
Diphenhydramine Injection Interactions
Interactions
Potentiates CNS depression with alcohol, other CNS depressants. Potentiates anticholinergic effects with MAOIs.
Diphenhydramine Injection Adverse Reactions
Adverse Reactions
Drowsiness, dizziness, anticholinergic effects, excitability in children.
Diphenhydramine Injection Clinical Trials
See Literature
Diphenhydramine Injection Note
Not Applicable
Diphenhydramine Injection Patient Counseling
See Literature
Diphenhydramine Injection Generic Name & Formulations
Legal Class
Rx
General Description
Diphenhydramine HCl 50mg/mL; for IV or IM inj.
Pharmacological Class
Antihistamine.
See Also
How Supplied
Contact supplier.
Manufacturer
Diphenhydramine Injection Indications
Indications
Motion sickness.
Diphenhydramine Injection Dosage and Administration
Adult
10–50mg IV or deep IM; max 400mg/day.
Children
Neonates: not recommended. Others: 5mg/kg per day in 4 divided doses IV or deep IM; max 300mg daily in 4 divided doses.
Diphenhydramine Injection Contraindications
Contraindications
Neonates. Premature infants. Nursing mothers.
Diphenhydramine Injection Boxed Warnings
Not Applicable
Diphenhydramine Injection Warnings/Precautions
Warnings/Precautions
Asthma. Lower respiratory disorders. Glaucoma. Hyperthyroidism. Hypertension. Cardiovascular disease. GI or urinary obstruction. Children. Pregnancy (Cat.B).
Diphenhydramine Injection Pharmacokinetics
See Literature
Diphenhydramine Injection Interactions
Interactions
Potentiates CNS depression with alcohol, other CNS depressants. Potentiates anticholinergic effects with MAOIs.
Diphenhydramine Injection Adverse Reactions
Adverse Reactions
Drowsiness, dizziness, anticholinergic effects, gastritis, paradoxical excitement, blood dyscrasias, hypotension.
Diphenhydramine Injection Clinical Trials
See Literature
Diphenhydramine Injection Note
Not Applicable
Diphenhydramine Injection Patient Counseling
See Literature
